Biodegradation is the process by which organic substances are broken down by the enzymes produced by living organisms. The term is often used in relation to ecology, waste management and environmental remediation (bioremediation). Organic material can be degraded aerobically, with oxygen, or anaerobically, without oxygen. A term related to biodegradation is biomineralisation, in which organic matter is converted into minerals. Biodegradable matter is generally organic material such as plant and animal matter and other substances originating from living organisms, or artificial materials that are similar enough to plant and animal matter to be put to use by microorganisms. Some microorganisms have the astonishing, naturally occurring, microbial catabolic diversity to degrade, transform or accumulate a huge range of compounds including hydrocarbons (e.g. oil), polychlorinated biphenyls (PCBs), polyaromatic hydrocarbons (PAHs), pharmaceutical substances, radionuclides and metals. Major methodological breakthroughs in microbial biodegradation have enabled detailed genomic, metagenomic, proteomic, bioinformatic and other high-throughput analyses of environmentally relevant microorganisms providing unprecedented insights into key biodegradative pathways and the ability of microorganisms to adapt to changing environmental conditions.[1]

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